Main factor...
Its really all about which component is a bottleneck, it can be your gfx card, cpu, hdd or otherwise, neither matters more than the other (wow is at 100% usage for me btw, amd 64 3700+ :X )
Tried windows 64 but the incompatibility with older programs is just.. blergh. Drivers in particular. Daemon tools sure as hell dont work with x64, at least they didnt back then.